There have been multiple clinical trials with PolyHeme® prior
to the initiation of the current pivotal Phase III prehospital trial.
Infusions have been given during resuscitation, intraoperatively
and postoperatively. The rate of infusion has varied with the clinical
setting. The most rapid rate consisted of the infusion of 20 units
in 20 minutes during rapid hemorrhage. This dose is equivalent to
two times the blood volume of an average adult.
